NEW PROCESS FOR THE PREPARATION OF DRONEDARONE

The subject of the present invention is a novel process for the preparation of N- [2-n-butyl-3-{4-[(3-dibutylamino)propoxy]benzoyl}-1-benzofuran-5- yl] methanesulfonamide of formula (I) and the new intermediates of the reparation process. La présente invention concerne, d'une part un nouveau pr...

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Bibliographic Details
Main Authors CSATARINE NAGY, MARIANNA, FRIESZ, ANTAL
Format Patent
LanguageEnglish
French
Published 14.07.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The subject of the present invention is a novel process for the preparation of N- [2-n-butyl-3-{4-[(3-dibutylamino)propoxy]benzoyl}-1-benzofuran-5- yl] methanesulfonamide of formula (I) and the new intermediates of the reparation process. La présente invention concerne, d'une part un nouveau procédé d'élaboration du méthane-sulfonamide de N-[2-n-butyl-3-{4-[(3-dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl] représenté par la formule (I), et d'autre part de nouveaux intermédiaires mis en oeuvre dans ce procédé d'élaboration.
Bibliography:Application Number: WO2010HU00143