CARBON NANOTUBE CONJUGATE FOR INHIBITING PATHOGENIC INFECTION STRUCTURES IN PLANTS

• Main Authors: CORREA JUNIOR, ARY, RODRIGUES, LEONARDO, LADEIRA, LUIZ ORLANDO
• Format: Patent
• Language: English; French; Portuguese
• Published: 07.07.2011
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MANUFACTURE OR TREATMENT THEREOF; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS; NANOTECHNOLOGY; PERFORMING OPERATIONS; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TRANSPORTING; TRAPPING; VINEGAR; WINE

The present invention describes the construction and use of a hybrid system involving the conjugation of carbon nanotubes and oligonucleotides. The more general aspect of said invention relates to the process and methodology for inhibiting or controlling pests and pathogenic infections in plants, especially in commercially important crops, such as beans, soya, coffee and eucalyptus. The oligonucleotide-carbon nanotube conjugate is used as a cell internalization agent carrying a specific nucleic acid sequence, also termed oligonucleotide, from outside into the pathogen cell cytoplasm. La présente invention concerne la construction et l'utilisation d'un système hybride impliquant la conjugaison de nanotubes de carbone et d'oligonucléotides. De manière générale, elle concerne un procédé et une technique d'inhibition ou d'élimination de nuisibles et d'infections par des pathogènes chez des végétaux, notamment dans des cultures présentant un important intérêt commercial, telles que le haricot, le soja, le café et l'eucalyptus. Le conjugué oligonucléotide-nanotubes de carbone est utilisé comme agent d'internalisation cellulaire transportant une séquence spécifique d'acide nucléique, également appelé oligonucléotide, de l'extérieur vers l'intérieur du cytoplasme de la cellule du pathogène. A presente invenção descreve a construção e uso de um sistema híbrido envolvendo a conjugação de nanotubos de carbono e oligonucleotídeos. Em seu aspecto mais geral relata processo e metodologia para a inibição ou controle de pragas e infecções de patógenos em vegetais, em especial, em culturas de importante interesse comercial tais como: feijão, soja, café e eucalipto. O conjugado oligonucleotídeo-nanotubos de carbono é utilizado como agente de internalização celular carreando uma seqüência específica de ácido nucléico, também denominado de oligonucleotídeo, de fora para dentro do citoplasma da célula do patógeno.