NOVEL ARYL UREA DERIVATIVE

There is a need for highly effective, orally administrable FAAH inhibitors, particularly agents for the prevention and treatment of pain. Disclosed is a novel aryl urea compound represented by general formula (I), salts or solvates thereof, and pharmaceutical compositions having the same as an activ...

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Bibliographic Details
Main Authors KAMINO TOMOYUKI, MAEDA YOSHITAKA
Format Patent
LanguageEnglish
French
Japanese
Published 30.06.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is a need for highly effective, orally administrable FAAH inhibitors, particularly agents for the prevention and treatment of pain. Disclosed is a novel aryl urea compound represented by general formula (I), salts or solvates thereof, and pharmaceutical compositions having the same as an active ingredient. The pharmaceutical composition is primarily for use in FAAH inhibitors, and agents for pain prevention and treatment. Selon l'invention, on a besoin d'inhibiteurs FAAH hautement efficaces, que l'on peut administrer par voie orale, en particulier des agents de prévention et de traitement de la douleur. L'invention concerne un nouveau composé d'aryl-urée représenté par la formule générale (I), des sels ou des solvates de celui-ci, ainsi que des compositions pharmaceutiques le comprenant comme principe actif. La composition pharmaceutique est essentiellement destinée à être utilisée dans des inhibiteurs FAAH, et des agents de prévention et de traitement de la douleur.
Bibliography:Application Number: WO2010JP73458