ACID ADDITION SALTS OF LENALIDOMIDE

The invention relates to acid addition salts of lenalidomide as well as to desirable polymorphic forms of lenalidomide hydrogen sulfate. Furthermore, the invention provides a process for producing acid addition salts of lenalidomide, which optionally can comprise a further step producing lenalidomid...

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Bibliographic Details
Main Authors MEERGANS, DOMINIQUE, ALBRECHT, WOLFGANG, BRUECK, SANDRA, PAETZ, JANA, STIEGEL, HANS-HUENTER
Format Patent
LanguageEnglish
French
Published 05.05.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to acid addition salts of lenalidomide as well as to desirable polymorphic forms of lenalidomide hydrogen sulfate. Furthermore, the invention provides a process for producing acid addition salts of lenalidomide, which optionally can comprise a further step producing lenalidomide in form of the free base. L'invention porte sur des sels d'addition d'acide du lénalidomide ainsi que sur des formes polymorphes recherchées d'hydrogénosulfate de lénalidomide. En outre, l'invention porte sur un procédé pour la production de sels d'addition d'acide du lénalidomide, qui peut éventuellement comprendre une étape supplémentaire produisant du lénalidomide sous la forme de la base libre.
Bibliography:Application Number: WO2010EP06595