PIPERIDINE DERIVATIVE AND ITS USE FOR THE TREATMENT OF DIABETS AND OBESITY

The present invention relates to the GPR119 agonist, N-(2-fluoro-4-(methylsulfonyl)phenyl)-5-methyl-6-(1-(5-methylpyrazin-2-yl)piperidin-4-yloxy)pyrimidin-4-amine (Compound 1, Formula (I)), and pharmaceutically acceptable salts, solvates, and hydrates thereof, that are useful in the treatment of GPR...

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Bibliographic Details
Main Authors JONES, ROBERT M, LEHMANN, JUERG
Format Patent
LanguageEnglish
French
Published 13.01.2011
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Summary:The present invention relates to the GPR119 agonist, N-(2-fluoro-4-(methylsulfonyl)phenyl)-5-methyl-6-(1-(5-methylpyrazin-2-yl)piperidin-4-yloxy)pyrimidin-4-amine (Compound 1, Formula (I)), and pharmaceutically acceptable salts, solvates, and hydrates thereof, that are useful in the treatment of GPR119-related disorders, such as, metabolic-related disorders and complications thereof, such as, diabetes and obesity. La présente invention porte sur l'agoniste du GPR119, la N-(2-fluoro-4-(méthylsulfonyl)phényl)-5-méthyl-6-(1-(5-méthylpyrazin-2-yl)pipéridin-4-yloxy)pyrimidin-4-amine (Composé 1, Formule (I)) et sur ses sels solvates et hydrates pharmaceutiquement acceptables, qui sont utiles dans le traitement de troubles associés à GPR119, tels que les troubles liés au métabolisme et leurs complications, comme le diabète et l'obésité.
Bibliography:Application Number: WO2010US41325