BIFUNCTIONAL POLYPEPTIDES

A bifunctional polypeptide comprising a specific binding partner for a peptide-MHC epitope, such as an antibody or a T cell receptor ("TCR"), and an immune effector, such as an antibody or a cytokine, the immune effector part being linked to the N- terminus of the peptide-MHC binding part....

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Bibliographic Details
Main Authors JAKOBSEN, BENT, KARSTEN, VUIDEPOT, ANNELISE, BRIGITTE
Format Patent
LanguageEnglish
French
Published 25.11.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:A bifunctional polypeptide comprising a specific binding partner for a peptide-MHC epitope, such as an antibody or a T cell receptor ("TCR"), and an immune effector, such as an antibody or a cytokine, the immune effector part being linked to the N- terminus of the peptide-MHC binding part. L'invention concerne un polypeptide bifonctionnel comprenant un partenaire de liaison spécifique pour un épitope peptide-MHC, tel qu'un anticorps ou un récepteur de lymphocyte T, et un effecteur immun, tel qu'un anticorps ou une cytokine, la partie effecteur immun étant liée à la terminaison N de la partie de liaison du peptide-MHC.
Bibliography:Application Number: WO2010GB00988