ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS

Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) or (II): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such...

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Bibliographic Details
Main Authors LINSELL, MARTIN, SHERINGHAM, GOLDBLUM, ADAM, AARON, AGGEN, JAMES, BRADLEY, DOZZO, PAOLA
Format Patent
LanguageEnglish
French
Published 25.08.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) or (II): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. L'invention porte sur des composés ayant une activité antibactérienne. Les composés ont la structure suivante (I) ou (II) : comprenant des stéréo-isomères, des sels et promédicaments pharmaceutiquement acceptables de ceux-ci, où Q1, Q2, Q3, R1, R2 et R3 sont tels que définis présentement. L'invention porte également sur des procédés associés à la préparation et à l'utilisation de tels composés, ainsi que sur des compositions pharmaceutiques comprenant de tels composés.
Bibliography:Application Number: WO2010US34884