PRODUCTION OF PROTEINS USING TRANSPOSON-BASED VECTORS

Novel compositions for the in vitro or in vivo production of specific proteins are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes for the protein of interest, and the transposon-based vectors comprising these comp...

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Bibliographic Details
Main Authors COOPER, RICHARD, K, FIORETTI, WILLIAM C
Format Patent
LanguageEnglish
French
Published 14.10.2010
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Summary:Novel compositions for the in vitro or in vivo production of specific proteins are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes for the protein of interest, and the transposon-based vectors comprising these components. Also provided are methods of making these compositions and methods of using these compositions for the production of desired proteins in vivo or in transfected cells in vitro. L'invention concerne de nouvelles compositions pour la production in vitro ou in vivo de protéines spécifiques. Les compositions contiennent des composants de vecteurs, tels qu'un squelette de vecteur, un promoteur et un gène d'intérêt qui code la protéine d'intérêt, et les vecteurs à base de transposon contiennent ces composants. L'invention concerne également des procédés de préparation de ces compositions et des procédés d'utilisation de ces compositions pour produire les protéines souhaitées in vivo ou dans des cellules transfectées in vitro.
Bibliography:Application Number: WO2010US30589