BISPECIFIC ANTI-HER ANTIBODIES

The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists. La présente invention concerne de...

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Bibliographic Details
Main Authors FUH, GERMAINE, SLIWKOWSKI, MARK, X, SCHAEFER, GABRIELE, HABER, LAURIC
Format Patent
LanguageEnglish
French
Published 23.09.2010
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists. La présente invention concerne des anticorps anti-HER, comprenant des anticorps anti-HER multi-spécifiques, des compositions les comprenant et des procédés d'utilisation de ces anticorps. L'invention concerne également des anticorps anti-EGFR/HER3 multi-spécifiques moins toxiques que les antagonistes traditionnels de l'EGFR.
Bibliography:Application Number: WO2010US28023