SUBSTITUTED PYRAZINONE AMIDES

The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. The variables R1, R2, R3 and R4 are as described herein. La présente invention concerne...

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Bibliographic Details
Main Authors PFEFFERKORN, JEFFREY ALLEN, BENBOW, JOHN WILLIAM
Format Patent
LanguageEnglish
French
Published 29.07.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. The variables R1, R2, R3 and R4 are as described herein. La présente invention concerne des composés de Formule (I) qui agissent en tant qu'activateurs de glucokinase ; des compositions pharmaceutiques les incluant ; et des méthodes de traitement de pathologies, de troubles ou d'états pathologiques faisant intervenir la glucokinase. Les variables R1, R2, R3 et R4 sont telles que décrites dans la présente invention.
Bibliography:Application Number: WO2010IB50035