PYRIMIDINE DERIVATIVES AS GPCR MODTTLATORS FOR USE IN THE TREATMENT OF OBESITY AND DIABETES

The present invention relates to Pyriraidine Derivatives of formula (I), compositions comprising a Pyrimidine Derivative, and methods of using the Pyrimidine Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a metabolic disorder, a cardiovascular disease or a disorde...

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Bibliographic Details
Main Authors XIA, YAN, NEUSTADT, BERNARD R, STAMFORD, ANDREW, HAO, JINSONG, JAYNE, CHARLES LEE
Format Patent
LanguageEnglish
French
Published 01.07.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to Pyriraidine Derivatives of formula (I), compositions comprising a Pyrimidine Derivative, and methods of using the Pyrimidine Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G protein -coupled receptor (GPCR) in a patient. La présente invention porte sur des dérivés de pyrimidine de formule (I), sur des compositions comprenant un dérivé de pyrimidine, et sur des procédés d'utilisation des dérivés de pyrimidine pour le traitement ou la prévention de l'obésité, du diabète, d'une complication diabétique, d'un trouble métabolique, d'une maladie cardiovasculaire ou d'un trouble lié à l'activité d'un récepteur couplé à une protéine G (RCPG) chez un patient.
Bibliography:Application Number: WO2009US68968