(3-OXO)PYRIDIN-4-YLUREA DERIVATIVES AS PDE4 INHIBITORS

New (3-oxo)pyridazin-4-ylurea derivatives having the chemcial structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of the phosphodiesterase IV (PDE4). La présente invention concerne de nou...

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Main Authors MORENO MOLLO, IMMACULADA, MONTSERRAT, PAGES SANTACANA, LLUIS, MIQUEL, GRACIA FERRER, JORDI, BUIL ALBERO, MARIA ANTONIA, ROBERTS, RICHARD, SPURRING, SEVILLA GOMEZ, SARA, TALTAVULL MOLL, JOAN
Format Patent
LanguageEnglish
French
Published 24.06.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:New (3-oxo)pyridazin-4-ylurea derivatives having the chemcial structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of the phosphodiesterase IV (PDE4). La présente invention concerne de nouveaux dérivés de (3-oxo)pyridazin-4-ylurée ayant la structure chimique de formule (I) ; ainsi qu'une méthode de préparation, des compositions pharmaceutiques les renfermant et leur utilisation en thérapie en tant qu'inhibiteurs de la phosphodiestérase IV (PDE4).
Bibliography:Application Number: WO2009EP08794