4-AMINO-5- (HETERO) ARYL-2-PHENYLAMINO-PYRIMIDINE OR PYRIDINE AND THEIR USE AS DNA GYRASE AND/OR TOPOISOMERASE IV INHIBITORS

Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described. L'invention porte sur les composé...

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Main Authors HULL, KENNETH, GREGORY, MANCHESTER, JOHN, IRVIN, MCGUIRE, HELEN, MAUREEN, BORIACK-SJODIN, ANN, MCKINNEY, DAVID, CHARLES, DUSSAULT, DAEMIAN, DAVID, HATOUM-MOKDAD, HOLIA, IOANNIDIS, GEORGINE, STOKES, SUZANNE, CARCANAGUE, DANIEL, ROBERT
Format Patent
LanguageEnglish
French
Published 27.05.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described. L'invention porte sur les composés de la formule (I) ainsi que sur les sels pharmaceutiquement acceptables associés. L'invention concerne également des procédés de préparation associés, des compositions pharmaceutiques contenant lesdits dérivés et leurs utilisations en tant que médicaments, ainsi que dans le traitement des infections bactériennes.
Bibliography:Application Number: WO2009GB51299