PYRROLIDINYL AND PIPERIDINYL COMPOUNDS USEFUL AS NHE-1 INHIBITORS

Disclosed are compounds of formula (I) and compositions of the present invention which are inhibitors of the sodium proton exchanger isoform-1 (NHE-I). Also disclosed are methods of using and making the same. L'invention porte sur des composés et des compositions qui sont des inhibiteurs de l&#...

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Bibliographic Details
Main Authors GUO, XIN, KIRRANE, THOMAS, MARTIN, BENTZIEN, JOERG, MARTIN, ELDRUP, ANNE, BETTINA, HUBER, JOHN, DAVID, SOLEYMANZADEH, FARIBA, BURKE, JENNIFER, SWINAMER, ALAN, DAVID, BOYER, STEPHEN, JAMES
Format Patent
LanguageEnglish
French
Published 14.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed are compounds of formula (I) and compositions of the present invention which are inhibitors of the sodium proton exchanger isoform-1 (NHE-I). Also disclosed are methods of using and making the same. L'invention porte sur des composés et des compositions qui sont des inhibiteurs de l'isoforme-1 de l'échangeur sodium-proton (NHE-1). L'invention porte également sur des procédés d'utilisation et de fabrication de ceux-ci.
Bibliography:Application Number: WO2009US48394