BIOSOLUBLE COATING COMPRISING ANTI-PROLIFERATIVE AND ANTI-INFLAMMATORY AGENT COMBINATION FOR TREATMENT OF VASCULAR DISORDERS

• Main Authors: LIM, FLORENCIA, MASLANKA, BOZENA, ZOFIA, HOSSAINY, SYED, F.A, NGO, MICHAEL, H, TROLLSAS, MIKAEL, O
• Format: Patent
• Language: English; French
• Published: 16.09.2010
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque. L'invention porte sur des systèmes d'administration de médicament tels que des endoprothèses vasculaires d'administration de médicament ayant un agent antiprolifératif tel que l'évérolimus et un agent anti-inflammatoire tel que le clobétasol. L'invention porte également sur des procédés de traitement d'un dysfonctionnement vasculaire tel que la resténose ou une plaque vulnérable.