CO-CRYSTALS OF DULOXETINE AND COX-INHIBITORS FOR THE TREATMENT OF PAIN

The present invention relates to co-crystals of duloxetine and co-crystal formers selected from COX-INHIBITORs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. Specific COX-INHIBITORS are naproxen and...

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Main Authors RAMIREZ ARTERO, JESUS, BUSCHMANN, HELMUT, HEINRICH, CERON BERTRAN, JORDI CARLES, BENET BUCHHOLZ, JORDI, SOLA CARANDELL, LLUIS
Format Patent
LanguageEnglish
French
Published 26.11.2009
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to co-crystals of duloxetine and co-crystal formers selected from COX-INHIBITORs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. Specific COX-INHIBITORS are naproxen and tolmetin. La présente invention concerne des co-cristaux de duloxétine et des agents de formation de co-cristaux choisis parmi les inhibiteurs de COX, des procédés pour leur préparation et leurs utilisations comme médicaments ou dans des formulations pharmaceutiques, plus particulièrement pour le traitement de la douleur. Les inhibiteurs de COX spécifiques sont le naproxène et la tolmétine.
Bibliography:Application Number: WO2009EP03617