METHODS FOR ENHANCING UTROPHIN PRODUCTION VIA INHIBITION OF MICRORNA

This invention provides a method for enhancing utrophin protein production in a cell by inhibiting an utrophin microRNA molecule. Moreover, the invention provides that methods for enhancing utrophin protein production in a muscle cell are used for treating a muscular dystrophy and/or other myopathie...

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Bibliographic Details
Main Authors KHURANA, TEJVIR, S, MOORWOOD, CATHERINE, BASU, UTPAL, PATEL, GOPAL, LOZYNSKA, OLGA
Format Patent
LanguageEnglish
French
Published 30.12.2009
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:This invention provides a method for enhancing utrophin protein production in a cell by inhibiting an utrophin microRNA molecule. Moreover, the invention provides that methods for enhancing utrophin protein production in a muscle cell are used for treating a muscular dystrophy and/or other myopathies. Cette invention porte sur un procédé pour améliorer la production de protéine utrophine dans une cellule par l'inhibition d'une molécule de microARN d'utrophine. De plus, l'invention porte sur des procédés pour améliorer la production de protéine utrophine dans une cellule musculaire, lesquels procédés sont utilisés pour traiter une dystrophie musculaire et/ou d'autres myopathies.
Bibliography:Application Number: WO2009US41783