METHOD FOR PREPARING ORTHO-DIHYDROXYISOFLAVONES USING A BIOTRANSFORMATION SYSTEM

• Main Authors: KIM, JUNE HYUNG, CHA, MIN-HO, RHO, HO SIK, PARK, HYE YOON, KIM, BYUNG GEE, ROH, CHANG HYUN, CHOI, KWON YOUNG, BISHNU, PRASAD PANDEY, PARK, JUN SEONG, CHANG, IH SEOP, KIM, DUCK HEE, SEO, SU HYUN
• Format: Patent
• Language: English; French
• Published: 29.10.2009
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Disclosed herein is a method for preparing ortho- dihydroxyisof lavones using a biotransformation system. More specifically, disclosed is a method for preparing ortho-dihydroxyisof lavones, which comprises biotransf orming daidzein or genistein by actinomycete microorganisms, particularly Streptomyces avermitilis, Nocardia farcinica or Streptomyces lincolnesis, in order to efficiently prepare ortho-dihydroxyisof lavones having an excellent antioxidant function and a whitening effect. La présente invention concerne un procédé de préparation d'ortho-dihydroxyisoflavones au moyen d'un système de biotransformation. Plus particulièrement, l'invention concerne un procédé de préparation d'ortho-dihydroxyisoflavones, lequel comprend la biotransformation de la daidzéine ou de la génistéine par des microorganismes actinomycètes, en particulier Streptomyces avermitilis, Nocardia farcinica ou Streptomyces lincolnesis, afin de préparer de manière efficace des ortho-dihydroxyisoflavones ayant une excellente fonction antioxydante et un excellent effet blanchissant.