OSTEOGENIC DIFFERENTIATION OF BONE MARROW STEM CELLS AND MESENCHYMAL STEM CELLS USING A COMBINATION OF GROWTH FACTORS

The invention relates to methods for osteogenic differentiation of human bone marrow stem cells (BMSC) or mesenchymal stem cells (MSC), in particular using human plasma or serum and FGF and TGFB growth factors. The invention also provides the so-obtained cells and cell populations, as well as furthe...

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Bibliographic Details
Main Authors PESESSE, XAVIER, BADOER, CINDY, BASTIANELLI, ENRICO
Format Patent
LanguageEnglish
French
Published 16.07.2009
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to methods for osteogenic differentiation of human bone marrow stem cells (BMSC) or mesenchymal stem cells (MSC), in particular using human plasma or serum and FGF and TGFB growth factors. The invention also provides the so-obtained cells and cell populations, as well as further products comprising such and uses thereof in bone therapy. L'invention porte sur des procédés de différenciation ostéogénique de cellules souches de moelle osseuse humaines (BMSC) ou de cellules souches mésenchymateuses (MSC), en particulier à l'aide de plasma ou sérum humain et de facteurs de croissance FGF et TGFB. L'invention porte également sur les cellules et populations de cellules ainsi obtenues ainsi que sur d'autres produits comprenant celles-ci et sur leurs utilisations en thérapie osseuse.
Bibliography:Application Number: WO2009EP50209