PHAGE ?-MRU POLYNUCLEOTIDES AND POLYPEPTIDES AND USES THEREOF

The invention encompasses phage ?mru including phage induction, phage particles, and the phage genome. Also encompassed are phage polypeptides, as well as polynucleotides which encode these polypeptides, expression vectors comprising these polynucleotides, and host cells comprising these vectors. Th...

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Main Authors ATTWOOD, GRAEME TREVOR, MOON, CHRISTINA DIANE, ALTERMANN, ERIC HEINZ, PETRUS, HENDRICUS, JANSSEN, LEAHY, SINEAD CHRISTINE, KELLY, WILLIAM JOHN, SCHOFIELD, LINLEY ROSE, RONIMUS, ROBERT STARR, TOOTILL, CATHERINE MARY, DONG, LI, KONG, ZHANHAO, DEY, DEBJIT, SANG, CARRIE
Format Patent
LanguageEnglish
French
Published 02.04.2009
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Summary:The invention encompasses phage ?mru including phage induction, phage particles, and the phage genome. Also encompassed are phage polypeptides, as well as polynucleotides which encode these polypeptides, expression vectors comprising these polynucleotides, and host cells comprising these vectors. The invention further encompasses compositions and methods for detecting, targeting, permeabilising, and inhibiting microbial cells, especially methanogen cells, using the disclosed phage, polypeptides, polynucleotides, expression vectors, or host cells. La présente invention concerne des particules jmru bactériophage comprenant l'induction de bactériophages, des particules de bactériophages, et le génome de bactériophages. L'invention concerne également des polypeptides de bactériophages, ainsi que des polynucléotides codant pour ces polypeptides, des vecteurs d'expression comportant ces polynucléotides, et des cellules hôtes comportant ces vecteurs. L'invention concerne en outre des compositions et des procédés permettant la détection, le ciblage, la perméabilisation, et l'inhibition de cellules microbiennes, notamment des cellules méthanogènes, au moyen du bactériophage, des polypeptides, des polynucléotides, des vecteurs d'expression, ou des cellules hôtes selon l'invention.
Bibliography:Application Number: WO2008NZ00248