DETECTION OF SALIVA PROTEINS MODULATED SECONDARY TO DUCTAL CARCINOMA IN SITU OF THE BREAST

A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method involves measuring the concentration of at least one protein biomarker selected from a group of forty-nin...

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Bibliographic Details
Main Authors BIGLER, LENORA, R, DUBINSKY, WILLIAM, P, STRECKFUS, CHARLES, F
Format Patent
LanguageEnglish
French
Published 18.06.2009
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Summary:A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method involves measuring the concentration of at least one protein biomarker selected from a group of forty-nine differentially expressed proteins in the saliva of persons with DCIS, or benign fibroadenoma, or in persons who are cancer-free. The resulting test data is compared to a reference panel. From the comparison the presence in the subject of either ductal carcinoma in situ of the breast, or benign fibroadenoma of the breast is determined.
Bibliography:Application Number: WO2008US75955