FR901464 AND ANALOGS WITH ANTITUMOR ACTIVITY AND METHOD FOR THEIR PREPARATION
The present invention provides analogs of FR901464, as well as a methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing. L'invention concer...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French |
| Published |
12.03.2009
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention provides analogs of FR901464, as well as a methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
L'invention concerne des analogues de FR901464 ainsi qu'un procédé de préparation de FR901464 et d'analogues de ce composé. Ces composés présentent une activité anticancéreuse et constituent des candidats pour traiter des états pathologiques associés à un dysfonctionnement de l'épissage d'ARN. |
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| AbstractList | The present invention provides analogs of FR901464, as well as a methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
L'invention concerne des analogues de FR901464 ainsi qu'un procédé de préparation de FR901464 et d'analogues de ce composé. Ces composés présentent une activité anticancéreuse et constituent des candidats pour traiter des états pathologiques associés à un dysfonctionnement de l'épissage d'ARN. |
| Author | ALBERT, BRIAN, J KOIDE, KAZUNORI SIVARAMAKRISHNAN, ANANTHAPADMANABHAN |
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| DocumentTitleAlternate | FR901464 ET ANALOGUES PRÉSENTANT UNE ACTIVITÉ ANTITUMORALE, ET PROCÉDÉ DE PRÉPARATION DE CES COMPOSÉS |
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| RelatedCompanies | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION ALBERT, BRIAN, J KOIDE, KAZUNORI SIVARAMAKRISHNAN, ANANTHAPADMANABHAN |
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| Snippet | The present invention provides analogs of FR901464, as well as a methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer... |
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| Title | FR901464 AND ANALOGS WITH ANTITUMOR ACTIVITY AND METHOD FOR THEIR PREPARATION |
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