ANTI-EPHA2 ANTIBODY

• Main Authors: OHTSUKA, TOSHIAKI, TAKIZAWA, TAKESHI, YAMAGUCHI, JUNKO, URANO, ATSUSHI, HASEGAWA, JUN, AGATSUMA, TOSHINORI, NAKAHARA, KAORI
• Format: Patent
• Language: English; French; Japanese
• Published: 05.03.2009
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Disclosed are: an antibody capable of inhibiting the canceration of a cell and/or the proliferation of a tumor cell; and others. Specifically disclosed are: an antibody which can recognize an epitope that can be recognized by an antibody produced by a hybridoma SH 348-1 (FERM BP-10836) or a hybridoma SH 357-1 (FERM BP-10837); an antibody produced by a hybridoma SH 348-1 or a hybridoma SH 357-1; an antibody which is produced by humanizing an antibody produced by a hybridoma SH 348-1 or a hybridoma SH 357-1; a pharmaceutical agent comprising any one of the aforementioned antibodies as an active ingredient; and others. La présente invention concerne un anticorps capable d'inhibition de la cancérisation d'une cellule et/ou la prolifération d'une cellule tumorale, et analogues. De manière spécifique, la présente invention concerne un anticorps pouvant reconnaître un épitope qui peut être reconnu par un anticorps produit par un hybridome SH 348-1 (FERM BP-10836) ou un hybridome SH 357-1 (FERM BP-10837); un anticorps produit par un hybridome SH 348-1 ou un hybridome SH 357-1; un anticorps produit par humanisation d'une anticorps produit par un hybridome SH 348-1 ou un hybridome SH 357-1; un agent pharmaceutique comportant un desdits anticorps en tant que principe actif, et analogues.