PHENYL CARBAMATES FOR TREATING GASTROINTESTINAL INFLAMMATION

• Main Authors: JUBEH, TAREQ TAHA, RUBINSTEIN, AVRAHAM, WEINSTOCK-ROSIN, MARTA
• Format: Patent
• Language: English; French
• Published: 19.02.2009
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention is directed to pharmaceutical compositions comprising inhibitors of acetylcholine esterase useful in methods for treating inflammatory diseases and autoimmune diseases of the gastrointestinal tract. In particular, the present invention provides pharmaceutical compositions comprising phenyl carbamates including rivastigmine that are known acetylcholine esterase inhibitors, now disclosed to be useful for treating inflammatory bowel disease and other autoimmune and chronic inflammatory gastrointestinal diseases and conditions. La présente invention concerne des compositions pharmaceutiques contenant des inhibiteurs d'acétylcholine estérase utiles dans les procédés destinés à traiter les maladies inflammatoires et les maladies auto-immunes de l'appareil gastro-intestinal. En particulier, la présente invention fournit des compositions pharmaceutiques contenant des carbamates de phényle comprenant la rivastigmine qui sont des inhibiteurs d'acétylcholine estérase connus, maintenant décrits comme étant utiles pour traiter les maladies intestinales inflammatoires et d'autres maladies et affections gastro-intestinales inflammatoires auto-immunes et chroniques.