RENIN INHIBITORS

Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic proteas...

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Main Authors DILLARD, LAWRENCE, W, YUAN, JING, SINGH, SURESH, B, ISHCHENKO, ALEXEY, V, MCGEEHAN, GERARD, TICE, COLIN, M, XU, ZHENRONG, CLAREMON, DAVID, A, FLAHERTY, PATRICK, T, SIMPSON, ROBERT, D, BALDWIN, JOHN, J, JIA, LANQI, ZHAO, WEI, CACATIAN, SALVACION
Format Patent
LanguageEnglish
French
Published 07.05.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof. L'invention concerne des composés qui se lient aux protéases aspartiques pour inhiber leur activité. Ils sont utiles dans le traitement ou l'atténuation des symptômes de maladies associées à l'activité des protéases aspartiques. L'invention concerne également des méthodes d'utilisation de ces composés pour le traitement ou l'atténuation des symptômes de troubles associés à l'activité des protéases aspartiques chez un sujet nécessitant un tel traitement.
Bibliography:Application Number: WO2008US07700