NOVEL PROCESS FOR PREPARATION OF ADAPALENE

Disclosed herein is a process for the preparation of the adamantyl derivative 6-[3-(l- Adamantyl) - 4 - methoxy phenyl] - 2 - naphthoic acid known as adapalene employing a novel intermediate 3 - Adamantyl - 4 - methoxyphenyl potassium trifluoroborate. L'invention porte sur un procédé pour la pr...

Full description

Saved in:
Bibliographic Details
Main Authors VYAS, KETAN, DHANSUKHLAL, PANANDIKAR, ADITI, MILIND, PATIL, ULHAS, DIGAMBAR, NALAWADE, PRAVIN, NAIR, RANJEET
Format Patent
LanguageEnglish
French
Published 23.10.2008
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:Disclosed herein is a process for the preparation of the adamantyl derivative 6-[3-(l- Adamantyl) - 4 - methoxy phenyl] - 2 - naphthoic acid known as adapalene employing a novel intermediate 3 - Adamantyl - 4 - methoxyphenyl potassium trifluoroborate. L'invention porte sur un procédé pour la préparation du dérivé adamantylé acide 6-[3-(l-adamantyl)-4-méthoxy, phényl]-2-naphtoïque, connu comme étant l'adapalène, dans lequel on utilise un nouvel intermédiaire, à savoir le 3-adamantyl-4-méthoxyphényl potassium trifluoroborate.
Bibliography:Application Number: WO2008IN00236