PROCESS FOR PRODUCTION OF L-AMINO ACID

An L-amino acid can be produced by culturing a microbial cell in a culture medium to produce and accumulate the L-amino acid in the culture medium or the microbial cell and then collecting the L-amino acid from the culture medium or the microbial cell, wherein the microbial cell is engineered as to...

Full description

Saved in:
Bibliographic Details
Main Authors IZUI, HIROSHI, NISHI, RANKO, NAKAMURA, JUN, HARA, YOSHIHIKO
Format Patent
LanguageEnglish
French
Japanese
Published 26.06.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:An L-amino acid can be produced by culturing a microbial cell in a culture medium to produce and accumulate the L-amino acid in the culture medium or the microbial cell and then collecting the L-amino acid from the culture medium or the microbial cell, wherein the microbial cell is engineered as to have an ability of producing the L-amino acid and also have a reduced succinate dehydrogenase activity and a reduced a-ketoglutarate dehydrogenase activity. Selon la présente invention, il est possible de produire un acide aminé L grâce à un procédé consistant à cultiver une cellule microbienne dans un milieu de culture en vue de produire et d'accumuler l'acide aminé L dans le milieu de culture ou la cellule microbienne, puis à recueillir l'acide aminé L présent dans le milieu de culture ou la cellule microbienne, la cellule microbienne étant conçue de manière à pouvoir produire l'acide aminé L et présentant des activités de succinate déshydrogénase et d'a-kétoglutarate déshydrogénase réduites.
Bibliography:Application Number: WO2007JP67387