OPHTHALMIC REBAMIPIDE SOLUTION

This invention relates to a homogeneous ophthalmic composition, in particular an aqueous solution, comprising (1) rebamipide; (2) a viscosity enhancer; (3) an isotonic agent; and (4) a buffer, which solution has a pH of between about 7 and about 9. The invention further relates to rebamipide solutio...

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Bibliographic Details
Main Authors FRITZE, ANDREAS, CORCELLE, KARINE
Format Patent
LanguageEnglish
French
Published 26.06.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to a homogeneous ophthalmic composition, in particular an aqueous solution, comprising (1) rebamipide; (2) a viscosity enhancer; (3) an isotonic agent; and (4) a buffer, which solution has a pH of between about 7 and about 9. The invention further relates to rebamipide solutions which have a chloride concentration of less than about 0.5 mM. L'invention porte sur une composition ophtalmique homogène, en particulier une solution aqueuse, comprenant (1) du rebamipide ; (2) un agent d'augmentation de la viscosité ; (3) un agent isotonique ; et (4) un tampon, laquelle solution a un pH se situant entre environ 7 et environ 9. L'invention porte en outre sur les solutions de rebamipide qui ont une concentration en chlorure de moins d'environ 0,5 mM.
Bibliography:Application Number: WO2007EP64276