THERMOPHILIC MICROORGANISMS FOR ETHANOL PRODUCTION

• Main Authors: RUDD, BRIAN, MERCIER, CLAIRE, MILNER, PAUL, CRIPPS, ROGER, ELEY, KIRSTIN, MARTIN, STEVE, ATKINSON, ANTHONY
• Format: Patent
• Language: English; French
• Published: 25.09.2008
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FODDER; FOODS OR FOODSTUFFS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HUMAN NECESSITIES; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGYGENERATION, TRANSMISSION OR DISTRIBUTION; SPIRITS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

A thermophilic microorganism is modified to permit the increased production of ethanol, wherein a first modification is the inactivation of the lactate dehydrogenase gene and a second modification upregulates the pyruvate dehydrogenase gene. L'invention concerne un microorganisme thermophile modifié pour permettre la production accrue d'éthanol, une première modification consistant à inactiver le gène de la lactate déshydrogénase et une seconde modification consistant à réguler à la hausse le gène de la pyruvate déshydrogénase.