METHOD FOR IDENTIFYING COMPOUNDS THAT ACT AS INSULIN-SENSITIZERS

• Main Authors: ANTHONY, JESSY, MARITA, ROSALIND, ADAIKALASAMY, GHATE, ADITEE, NEMMANI, KUMAR, VENKATA SUBRAHMANYA, KELKAR, ADITYA, GANGOPADHYAY, ASHOK KUMAR, SHARMA, SOMESH, BHUMRA, SUJIT KAUR, DEKA, NABAJYOTI
• Format: Patent
• Language: English; French
• Published: 27.03.2008
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The present invention relates to a method for identifying compounds that act as insulin-sensitizers. The method can include screening of test compounds in two assays of insulin sensitivity. This method can identify lead compounds for the treatment of disorders caused by insulin resistance to glucose uptake. This invention also includes methods for treating insulin resistance and related disorders. L'invention concerne un procédé d'identification de composés agissant en tant que sensibilisateurs à l'insuline. Le procédé consiste notamment à cribler des composés test dans deux analyses de la sensibilité à l'insuline. Ce procédé permet d'identifier des composés du plomb destinés au traitemetn de troubles provoqués par la résistance à l'insuline à l'absorption du glucose. L'invention concerne également des procédés de traitement de résistance à l'insuline et des troubles associés.