HUMAN ANTI-FOLATE RECEPTOR ALPHA ANTIBODIES AND ANTIBODY FRAGMENTS FOR THE RADIOIMMUNOTHERAPY OF OVARIAN CARCINOMA

• Main Authors: CANEVARI, SILVANA, MAURIZI, GIOVANNI, FIGINI, MARIANGELA, CATTOZZO, MARGHERITA, MARTIN, FRANCK, DI CIOCCIO VITO
• Format: Patent
• Language: English; French
• Published: 20.03.2008
• Subjects: CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES

Antibody or fragment thereof, which specifically binds to folate receptor-alpha (FRa), wherein said antibody or fragment thereof comprises a light chain whose variable region comprises at least one of the following amino acid sequences : - RASESVSFLGINLIH (SEQ ID NO: 3), - QASNKDT (SEQ ID NO: 4), -...