ANTI-TUMOR AGENT
A therapeutic agent for removing a CD10-expressing cell from the body of a patient is expected to be useful as a therapeutic agent for a cancer such as lymphoma and leukemia in which CD10 is expressed or an inflammatory disease associated with a CD10-expressing cell (a B cell, a neutrophil). However...
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Main Authors | , , , , |
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Format | Patent |
Language | English French Japanese |
Published |
06.03.2008
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Subjects | |
Online Access | Get full text |
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Summary: | A therapeutic agent for removing a CD10-expressing cell from the body of a patient is expected to be useful as a therapeutic agent for a cancer such as lymphoma and leukemia in which CD10 is expressed or an inflammatory disease associated with a CD10-expressing cell (a B cell, a neutrophil). However, a patient who has been received the administration of an anti-tumor agent comprising an anti-CD20 antibody as an active ingredient continuously shows the resistance to the anti-tumor agent, and therefore the effect of the treatment in the patient is reduced. Thus, provided is an anti-tumor agent which is effective in a patient who has been received the administration of an anti-tumor agent comprising an anti-CD20 antibody as an active ingredient continuously.
L'invention concerne un agent thérapeutique pour extraire une cellule exprimant CD10 du corps d'un patient, lequel agent pourrait être utile en tant qu'agent thérapeutique pour un cancer, tel qu'un lymphome et une leucémie, dans lesquels CD10 est exprimé, ou une maladie inflammatoire associée à une cellule exprimant CD10 (un lymphocyte B, un neutrophile). Cependant, un patient auquel a été administré un agent anti-tumoral comprenant un anticorps anti-CD20 en tant qu'ingrédient actif montre de façon continue la résistance à l'agent anti-tumoral, et par conséquent l'effet du traitement chez le patient est réduit. Ainsi, l'invention concerne un agent anti-tumoral qui est efficace chez un patient auquel a été administré un agent anti-tumoral comprenant un anticorps anti-CD20 en tant qu'ingrédient actif de façon continue. |
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Bibliography: | Application Number: WO2007JP66685 |