BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES

Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein A, Q1, Q2, Q3, R3, and R4 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, o...

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Main Authors HUGHES, PHILIP, BARTA, THOMAS, OMMEN, ANDY, VEAL, JAMES, HUANG, KENNETH, HE, MA, WEI, WOODWARD, ANGELA
Format Patent
LanguageEnglish
French
Published 28.02.2008
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Summary:Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein A, Q1, Q2, Q3, R3, and R4 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds. La présente invention porte sur des composés et des sels de qualité pharmaceutique de Formule I, A, Q1, Q2, Q3, R3 et R4étant tels que définis dans l'invention. Les composés de Formule I peuvent être employés dans le traitement de maladies et/ou d'états pathologiques liés à la prolifération cellulaire, par exemple le cancer, les inflammations, l'arthrite, l'angiogenèse, ou similaire. La présente invention concerne également des compositions pharmaceutiques comprenant les composés selon l'invention et des méthodes de traitement des états pathologiques susmentionnés par emploi de tels composés.
Bibliography:Application Number: WO2007US76755