INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE

The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as...

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Bibliographic Details
Main Authors HURLEY, TIMOTHY, BRIAN, WATTANASIN, SOMPONG, PEUKERT, STEFAN
Format Patent
LanguageEnglish
French
Published 31.01.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as bacterial infection. La présente invention concerne des composés qui sont des inhibiteurs sélectifs et/ou puissants de l'UPPS. En plus des composés qui inhibent l'UPPS, l'invention concerne également des compositions pharmaceutiques comprenant ces composés et des procédés d'utilisation de ces composés pour le traitement d'une maladie bactérienne, telle qu'une infection bactérienne.
Bibliography:Application Number: WO2007US74303