INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF
Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-a) in a subject in need thereof. Cette invention concerne des...
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| Main Authors | , , , , , , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
12.02.2009
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-a) in a subject in need thereof.
Cette invention concerne des composés d'acide benzimidazole, indole et benzolactame boronique, des analogues de ces composés, des formulations pharmaceutiques, ainsi que des méthodes d'utilisation correspondantes pour inhiber les cytokines inflammatoires telles que le facteur de nécrose tumorale alpha (TNF-a) chez un sujet nécessitant un tel traitement. |
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| AbstractList | Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-a) in a subject in need thereof.
Cette invention concerne des composés d'acide benzimidazole, indole et benzolactame boronique, des analogues de ces composés, des formulations pharmaceutiques, ainsi que des méthodes d'utilisation correspondantes pour inhiber les cytokines inflammatoires telles que le facteur de nécrose tumorale alpha (TNF-a) chez un sujet nécessitant un tel traitement. |
| Author | JONES, MICHAEL, L BURNS, JAMES, F DIDSBURY, JOHN, R MATHEW, JESSYMOL LI, FRANCINE, F MARKWORTH, CHRISTOPHER, J HAYDAR, SIMON, N SCICINSKI, JAN, J DYAKONOV, TATYANA MIDDLEMISS, DAVID, N COLLUPY, GLENN, C SCHOENEN, FRANK, J VANVLIET, DAVID, N CABANA, LEONARD, A |
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| Title | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF |
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