POLYMER SUBMICRON PARTICLE PREPARATION BY SURFACTANT- MEDIATED PRECIPITATION

• Main Authors: YANG, NAN, LOH, SU, KAI
• Format: Patent
• Language: English; French
• Published: 24.07.2008
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION; TECHNICAL SUBJECTS COVERED BY FORMER USPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

The present invention is directed to methods for the fabrication of polymer nanoparticles comprising the addition of polymer solutions to aqueous solutions containing surfactants, wherein the concentration of the surfactants in the aqueous solution are lower than the critical micelle concentration of the surfactants. The methods of the present invention provide for the precipitation of uniformly dispersed polymer particles in the submicron size range, preferably from about 5 nm to about 100 nm. La présente invention concerne des procédés de fabrication de nanoparticules polymères comprenant l'ajout de solutions polymères à des solutions aqueuses contenant des tensioactifs, la concentration des tensioactifs dans la solution aqueuse étant inférieure à la concentration micellaire critique des surfactants. Les procédés selon la présente invention permettent la précipitation de particules polymères uniformément dispersées d'une taille submicronique, de préférence d'environ 5 nm à environ 100 nm.