ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE

Duloxetine intermediates of formulae (I) and (II), processes for their preparation, and their conversion to pharmaceutically acceptable salts of duloxetine are described. L'invention concerne des produits intermédiaires de duloxétine, des procédés de préparation de ces produits intermédiaires e...

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Bibliographic Details
Main Authors INI, SANTIAGO, SHMUELY, YARON
Format Patent
LanguageEnglish
French
Published 21.12.2007
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Duloxetine intermediates of formulae (I) and (II), processes for their preparation, and their conversion to pharmaceutically acceptable salts of duloxetine are described. L'invention concerne des produits intermédiaires de duloxétine, des procédés de préparation de ces produits intermédiaires et leur conversion en sels de duloxétine pharmaceutiquement acceptables.
Bibliography:Application Number: WO2007US09363