SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY

The present invention relates to substituted ring fused azines and methods of using said compounds in treating cancers. More specifically, the present invention relates to the preparation of 4-alkyl-2-(heterocyclic)-azines and their use as cancer agents or drugs for cancer therapy. The compounds of...

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Bibliographic Details
Main Authors SUTHERLAND, HAMISH, SCOTT, BAGULEY, BRUCE, CHARLES, MARSHALL, ELAINE, SHIRLEY, DENNY, WILLIAM, ALEXANDER
Format Patent
LanguageEnglish
French
Published 18.10.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Summary:The present invention relates to substituted ring fused azines and methods of using said compounds in treating cancers. More specifically, the present invention relates to the preparation of 4-alkyl-2-(heterocyclic)-azines and their use as cancer agents or drugs for cancer therapy. The compounds of the invention display favourable in vivo and in vitro activity against selected cancers. La présente invention concerne des azines à noyau condensées et substituées et les procédés d'utilisation desdits composés pour le traitement de cancers. Plus spécifiquement, la présente invention concerne la préparation de 4-alkylazines hétérocycliques en position 2 et leur utilisation en tant qu'agents ou médicaments anti-cancéreux dans une thérapie anti-cancéreuse. Les composés de l'invention présentent une activité avantageuse in vivo et in vitro contre certains cancers.
Bibliography:Application Number: WO2007NZ00077