PROCESS FOR PREPARING A LEUKOTRIENE ANTAGONIST
Process for preparing montelukast or a pharmaceutically acceptable salt thereof, especially its sodium salt, that comprises the condensation of an aldehyde and 7-chloro-2-methylquinoline. Moreover, novel intermediates useful for the synthesis of montelukast are described as well as their preparation...
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Main Authors | , , , , |
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Format | Patent |
Language | English French |
Published |
13.09.2007
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Subjects | |
Online Access | Get full text |
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Abstract | Process for preparing montelukast or a pharmaceutically acceptable salt thereof, especially its sodium salt, that comprises the condensation of an aldehyde and 7-chloro-2-methylquinoline. Moreover, novel intermediates useful for the synthesis of montelukast are described as well as their preparation.
La présente invention concerne un procédé de préparation de montélukast ou d'un sel pharmaceutiquement acceptable de celui-ci, plus particulièrement son sel de sodium, qui comprend la condensation d'un aldéhyde et de 7-chloro-2-méthylquinoléine. En outre, l'invention concerne de nouveaux intermédiaires utiles dans la synthèse de montélukast ainsi que leur préparation. |
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AbstractList | Process for preparing montelukast or a pharmaceutically acceptable salt thereof, especially its sodium salt, that comprises the condensation of an aldehyde and 7-chloro-2-methylquinoline. Moreover, novel intermediates useful for the synthesis of montelukast are described as well as their preparation.
La présente invention concerne un procédé de préparation de montélukast ou d'un sel pharmaceutiquement acceptable de celui-ci, plus particulièrement son sel de sodium, qui comprend la condensation d'un aldéhyde et de 7-chloro-2-méthylquinoléine. En outre, l'invention concerne de nouveaux intermédiaires utiles dans la synthèse de montélukast ainsi que leur préparation. |
Author | GORDO CAMPON, ESTHER BESSA BELLMUNT, JORDI VERDAGUER ESPAULELLA, XAVIER RAFECAS JANE, LLORENC PASTO AGUILA, MIREIA |
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DocumentTitleAlternate | PROCÉDÉ DE PRÉPARATION D'UN ANTAGONISTE DES LEUCOTRIÈNES |
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RelatedCompanies | GORDO CAMPON, ESTHER BESSA BELLMUNT, JORDI FARMAPROJECTS, S. A VERDAGUER ESPAULELLA, XAVIER RAFECAS JANE, LLORENC PASTO AGUILA, MIREIA |
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Title | PROCESS FOR PREPARING A LEUKOTRIENE ANTAGONIST |
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