AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

Disclosed herein is a novel class of aminophenyl compounds having the structure: Formula (I) wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto. La présen...

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Main Authors BADALASSI, FABRIZIO, SCHLIENGER, NATHALIE, THYGESEN, MIKKEL BOAS, LUND, BIRGITTE WINTHER, PAWLAS, JAN, LEWINSKY, RASMUS, OLSSON, ROGER
Format Patent
LanguageEnglish
French
Published 16.08.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed herein is a novel class of aminophenyl compounds having the structure: Formula (I) wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto. La présente invention concerne une nouvelle classe de composés aminophényle de formule (I) dans laquelle R1 représente cyano ou nitro et le cycle A est un hétérocycle ponté bicyclique ou tricyclique, ainsi que l'utilisation de ces composés comme modulateurs du récepteur d'androgène pour traiter ou prévenir des pathologies liées à celui-ci.
Bibliography:Application Number: WO2007US03070