ADENOVIRAL VECTOR-BASED MALARIA VACCINES
The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as Plasmodium nucleic acid sequences, operably linked to promoters. The invention further provides a method of inducing an immune response against malaria i...
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| Main Authors | , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
08.03.2007
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as Plasmodium nucleic acid sequences, operably linked to promoters. The invention further provides a method of inducing an immune response against malaria in a mammal comprising administering the adenoviral vectors to the mammal.
L'invention concerne des vecteurs adénoviraux constitués d'un génome adénoviral contenant des séquences nucléotidiques codant pour un antigène hétérologue, telles que des séquences nucléotidiques de Plasmodium, liées fonctionnellement à des promoteurs. Cette invention concerne également un procédé pour induire une réponse immunitaire contre la malaria chez un mammifère, qui consiste à administrer ces vecteurs adénoviraux au mammifère. |
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| AbstractList | The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as Plasmodium nucleic acid sequences, operably linked to promoters. The invention further provides a method of inducing an immune response against malaria in a mammal comprising administering the adenoviral vectors to the mammal.
L'invention concerne des vecteurs adénoviraux constitués d'un génome adénoviral contenant des séquences nucléotidiques codant pour un antigène hétérologue, telles que des séquences nucléotidiques de Plasmodium, liées fonctionnellement à des promoteurs. Cette invention concerne également un procédé pour induire une réponse immunitaire contre la malaria chez un mammifère, qui consiste à administrer ces vecteurs adénoviraux au mammifère. |
| Author | LIMBACH, KEITH KOVESDI, IMRE ETTYREDDY, DAMODAR, R KING, C., RICHTER CARUCCI, DANIEL, JOHN BRUDER, JOSEPH, T DOOLAN, DENISE, LOUISE MCVEY, DUNCAN, L |
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| DocumentTitleAlternate | VACCINS CONTRE LA MALARIA A BASE DE VECTEURS ADENOVIRAUX |
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| Notes | Application Number: WO2006US33982 |
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| RelatedCompanies | GENVEC, INC LIMBACH, KEITH KOVESDI, IMRE ETTYREDDY, DAMODAR, R KING, C., RICHTER CARUCCI, DANIEL, JOHN THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY NAVAL MEDICAL RESEARCH CENTER BRUDER, JOSEPH, T DOOLAN, DENISE, LOUISE MCVEY, DUNCAN, L |
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| Snippet | The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as Plasmodium... |
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| Title | ADENOVIRAL VECTOR-BASED MALARIA VACCINES |
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