MULTIPLEX DETERMINATION OF LIPID SPECIFIC BINDING MOIETIES

To perform large-scale multiplex analysis of lipid-specific binding, lipid microarrays were developed. Lipids identified as disease associated, or analogs there, can be tolerogenic to patients suffering from autoimmune disease. Lipid array analysis has revealed anti-lipid antibodies in patients with...

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Bibliographic Details
Main Authors STEINMAN, LAWRENCE, ROBINSON, WILLIAM H, KANTER, JENNIFER L
Format Patent
LanguageEnglish
French
Published 29.11.2007
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:To perform large-scale multiplex analysis of lipid-specific binding, lipid microarrays were developed. Lipids identified as disease associated, or analogs there, can be tolerogenic to patients suffering from autoimmune disease. Lipid array analysis has revealed anti-lipid antibodies in patients with immune disorders, and may contribute to the pathogenesis of disease. Pour effectuer une analyse multiplexée à grande échelle de fixation spécifique aux lipides, on a développé des microréseaux de lipides. Les lipides identifiés comme étant associés à une maladie, ou leurs analogues peuvent être tolérogènes pour des patients souffrant d'une maladie auto-immune. L'analyse des réseaux de lipides a révélé chez des patients présentant des troubles immunitaires la présence d'anticorps antilipides, ce qui peut contribuer à une pathogenèse de leur maladie.
Bibliography:Application Number: WO2006US28306