BETA-LACTAMYL PHENYLALANINE, CYSTEINE, AND SERINE VASOPRESSIN ANTAGONIST

Substituted 2-(azetidin-2-on-l-yl)alkoxyalkylalkanoic acids and 2-(azetidin-2-on-l-yl)arylalkylalkanoic acids, and analogs and derivatives thereof are described. Methods for using the described compounds, and pharmaceutical compositions thereof, to treat disease states responsive to antagonism of on...

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Bibliographic Details
Main Authors KOPPEL, GARY, A, MILLER, MARVIN, J, GUILLON, CHRISTOPHE, D
Format Patent
LanguageEnglish
French
Published 25.01.2007
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Summary:Substituted 2-(azetidin-2-on-l-yl)alkoxyalkylalkanoic acids and 2-(azetidin-2-on-l-yl)arylalkylalkanoic acids, and analogs and derivatives thereof are described. Methods for using the described compounds, and pharmaceutical compositions thereof, to treat disease states responsive to antagonism of one or more vasopressin receptors are also described. L'invention concerne des acides (azétidin-2-on-l-yl)alcoxyalkylalcanoïques substitués en position 2 et des acides (azétidin-2-on-l-yl)arylalkylalcanoïques, ainsi que des analogues et des dérivés de ceux-ci. Elle porte également sur des procédés d'utilisation desdits composés, desdites compositions pharmaceutiques pour traiter des maladies sensibles à l'antagonisme à un ou plusieurs récepteurs de vasopressine.
Bibliography:Application Number: WO2006US27703