ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE

The invention relates to a scalable biocatalytic process for the preparation of S- 1,1,1- trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast. L'invention concerne un procédé biocatalytique modulable de...

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Bibliographic Details
Main Authors KUPFER, ERNST, DOSWALD, STEPHAN, HANLON, STEVEN PAUL
Format Patent
LanguageEnglish
French
Published 18.01.2007
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a scalable biocatalytic process for the preparation of S- 1,1,1- trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast. L'invention concerne un procédé biocatalytique modulable de préparation of S-1,1,1-trifluoro-2-propanol à excès énantiomérique > 99 %, par réduction microbienne asymétrique de 1,1,1-trifluoroacétone au moyen de levure de boulangerie.
Bibliography:Application Number: WO2006EP63621