DI-SUBSTITUTED OXADIAZOLES AS CXC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are compounds of the formula (1). and the pharmaceutically acceptable salts thereof. X is N or N+O-, and Y is N or N+O-, provided that at least X or Y is N. The compounds are useful for the treatment of chemokine-mediated diseases such as COPD. La présente invention se rapporte à des compo...

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Bibliographic Details
Main Author PURAKKATTLE, BIJU, J
Format Patent
LanguageEnglish
French
Published 22.02.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds of the formula (1). and the pharmaceutically acceptable salts thereof. X is N or N+O-, and Y is N or N+O-, provided that at least X or Y is N. The compounds are useful for the treatment of chemokine-mediated diseases such as COPD. La présente invention se rapporte à des composés représentés par la formule (1) ainsi qu'à des sels pharmaceutiquement acceptables de ces composés. Dans ladite formule X est N ou N+O-, et Y est N ou N+O-, à condition qu'au moins X ou Y soit N. Ces composés s'avèrent utiles pour le traitement des maladies à médiation par des chimiokines, par exemple la broncho-pneumopathie chronique obstructive (PBCO).
Bibliography:Application Number: WO2006US25199