CHEMOKINE RECEPTOR BINDING COMPOUNDS

The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. Thesd compounds demonstrate protective effects against infec...

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Main Authors ZHOU, YUANXI, MCEACHERN, ERNEST, J, LI, TONG-SHUANG, HARWIG, CURTIS, SKERLJ, RENATO, T, METZ, MARKUS, BAIRD, IAN, R, BOURQUE, ELYSE, YANG, WEN, LANGILLE, JONATHAN, ZHU, YONGBAO
Format Patent
LanguageEnglish
French
Published 07.06.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. Thesd compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV). La présente invention concerne des composés de liaison au récepteur de la chimiokine, des compositions pharmaceutiques et leur utilisation. Plus spécifiquement, cette invention a pour objet des modulateurs de l'activité du récepteur de la chimiokine, de préférence, des modulateurs de CCR5. Ces composés présentent des effets protecteurs contre une infection de cellules cibles par un virus de l'immunodéficience humaine (VIH).
Bibliography:Application Number: WO2006US23125