SEMA4D IN CANCER DIAGNOSIS, DETECTION AND TREATMENT

• Main Authors: LAI, ALBERT, ROWE, MICHAEL, XU, XIE, TSE, CHRISTIN, YU, GUOYING, FANIDI, ABDALLAH, MOLER, EDWARD, BOOHER, ROBERT N
• Format: Patent
• Language: English; French
• Published: 19.10.2006
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the SEM A4D gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the SEMA4D gene. La présente invention concerne des gènes associés au cancer. Plus spécifiquement, l'invention concerne des méthodes de détection du cancer ou de la probabilité de développer un cancer en fonction de la présence ou de l'absence du gène SEMA4D ou de protéines codées par ledit gène. L'invention concerne également des méthodes et des molécules permettant de réguler ou de réguler négativement le gène SEMA4D.