MODIFIED RELEASE CIPROFLOXACIN COMPOSITIONS

Controlled release tablets comprising ciprofloxacin, with hardness and friability of the said tablets ranges between 10 to 70 kiloponds and less than 2% respectively, the compositions releasing at least 80 percent of the total amount of the ciprofloxacin into a pH 1.2 aqueous dissolution medium with...

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Main Authors GORE, SUBHASH, PANDURANG, NASARE, VIJAY, DINANATH, MOHAN, MAILATUR, SIVARAMAN, VERMA, SANJAY, BHUSHAN, INDU
Format Patent
LanguageEnglish
French
Published 03.08.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Controlled release tablets comprising ciprofloxacin, with hardness and friability of the said tablets ranges between 10 to 70 kiloponds and less than 2% respectively, the compositions releasing at least 80 percent of the total amount of the ciprofloxacin into a pH 1.2 aqueous dissolution medium within about 1 hour. L'invention se rapporte à des comprimés à libération contrôlée comportant de la ciprofloxacine, lesdits comprimés présentant une dureté comprise entre 10 et 70 kilogrammes-force et une friabilité inférieure à 2 %, ces compositions libérant au moins 80 % de la quantité totale de la ciprofloxacine dans un milieu de dissolution aqueux à un pH de 1,2 en approximativement 1 heure.
Bibliography:Application Number: WO2005US43656