RIZATRIPTAN PROCESS

Rizatriptan is prepared by reacting 4-hydrazinophenylmethyl-1,2,4-triazole dihydrochloride with 4-N,N-dimethylaminobutanal dimethylacetal in the presence of hydrochloric acid. L'invention concerne un procédé de préparation de rizatriptan, consistant à faire réagir du 4-hydrazinophénylméthyl-1,2...

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Main Authors REDDY, BHIMAVARAPU SRINIVASA, SEBASTIAN, SONNY, SARMA, PERI SEETHA RAMA, CHITRE, SAURABH, SHASHIKANT, KUMAR, SANKINENI SAMPATH, REDDY, PADI PRATAP
Format Patent
LanguageEnglish
French
Published 18.05.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Rizatriptan is prepared by reacting 4-hydrazinophenylmethyl-1,2,4-triazole dihydrochloride with 4-N,N-dimethylaminobutanal dimethylacetal in the presence of hydrochloric acid. L'invention concerne un procédé de préparation de rizatriptan, consistant à faire réagir du 4-hydrazinophénylméthyl-1,2,4-triazole dichlorhydrate avec du 4-N,N-diméthylaminobutanal diméthylacétal en présence d'acide chlorhydrique.
Bibliography:Application Number: WO2005US40718