METHODS OF TREATING METABOLIC DISORDERS BY MODULATION OF SALT-INDUCIBLE SERINE/THREONINE KINASE 2

• Main Author: ORT, TATIANA, A
• Format: Patent
• Language: English; French
• Published: 25.01.2007
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention relates to salt-inducible serine/threonine kinase polypeptides that are targets of small molecule drugs and that have properties relates to stimulation of biochemical or physiological responses in a cell, a tissue, an organ or an organism. Methods of use encompass screening, diagnostic and prognostic assay procedures as well as methods of treating diverse metabolic disorders. L'invention concerne des polypeptides de sérine/thréonine kinase inductible par des sels, lesquels sont des cibles de médicaments à petites molécules et lesquels possèdent des propriétés liées à la stimulation de réponses biochimiques ou physiologiques dans une cellule, un tissu, un organe ou un organisme. Des procédés d'utilisation comprennent des procédures de criblage, de diagnostic et de pronostic ainsi que des procédés de traitement de divers troubles métaboliques.